VPAC's Members are:

• Deakin University
• La Trobe University
• Monash University
• RMIT University
• Swinburne University of Technology
• The University of Ballarat
• The University of Melbourne
• Victoria University

VPAC also collaborates closely with organisations and institutions including;

• APAC
• Argonne National Laboratory
• Australian Computational Earth Systems Simulator (ACcESS)
• Bio21
• California Institute of Technology
• CSIRO
• Victorian Department of Primary Industries
• Victorian Department of Sustainability and Environment
• Holden Innovation
• IBM
• Land Victoria
• plm
• The University of Texas
• Victorian Bioinformatics Consortium